Information You Need: Vaccine Update

Two vaccine candidates created by Pfizer and Moderna have completed their phase three trials during November. Although results from these trials are preliminary and do not contain exact information regarding how long immunity would last, they are very promising. Plans for distributing the vaccine are still in progress, but frontline healthcare workers are likely to receive the first doses. Vaccine production will need to keep up with high demand, so stay up to date with AZCOVIDTXT  for any new information regarding the vaccine. Use the table below for more information regarding the Pfizer and Moderna vaccine candidates:

PfizerModernaWhat you need to know
Phase three trial efficacy:95% efficacy94.5% efficacyEfficacy refers to the percentage of disease reduced in  the vaccinated group compared to the placebo group. 
 
For comparison, 95% efficacy is almost equally as effective as the MMR vaccine (e.g., 97% effective after 2 doses), and much more effective than the seasonal flu vaccine, which ranges from 40-60% effectiveness each year.
Phase three results:Over 44,000 total volunteers


Half received two doses of the vaccine, the other half received a placebo


170 volunteers tested positive for COVID-19, only 8 of which were in the vaccinated group
30,000 total volunteers

Half received two doses of the vaccine, the other half received a placebo

95 total volunteers tested positive for COVID-19, only 5 of which received the vaccine

11 cases of severe COVID-19 in the placebo group
Few positive COVID-19 cases in the vaccination group speaks to the effectiveness of both vaccine candidates
Number of doses needed and timing:Two doses, 21 days apartTwo doses, 28 days apartIt is essential to take the same vaccine for both doses. So be sure to ask and remember which vaccine you received first or work with the same healthcare provider to receive both doses.


It is also important to take both doses. The second dose will “boost” the immune system and make it respond stronger if it encounters the actual virus.
Known side effects:Pain at injection site


Fatigue


Body aches (1-2 days)
Pain at injection site


Fatigue


Body aches (1-2 days)
The reported side effects are mild to moderate and appear to be similar to side effects experienced from a flu shot.
Must be stored at:Minus 75 degrees celsiusMinus 20 degrees celsiusHow the vaccine is stored impacts how the vaccine is distributed. If it can be stored at minus 20 that means it is easier to get to remote areas for distribution and won’t require expensive equipment.

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